What is Zagam (sparfloxacin)?
Sparfloxacin is an antibiotic in a class of drugs called fluoroquinolones. It fights bacteria in the body.
Sparfloxacin is used to treat various types of bacterial infections.

What is the most important information I should know about Zagam (sparfloxacin)?
Sparfloxacin has been withdrawn from the U.S. market.
Take all of the sparfloxacin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Take sparfloxacin with a full glass of water (8 ounces). Drink several extra glasses of fluid each day to prevent sparfloxacin crystals from forming in the urine. Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 4 hours after a dose of sparfloxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of sparfloxacin can greatly decrease the effects of the antibiotic.
What should I discuss with my healthcare provider before taking Zagam (sparfloxacin)?
Before taking this medication, tell your doctor if you have
• kidney disease;
• any kind of heart disease or heart problem; or
• seizures or epilepsy.
You may not be able to take sparfloxacin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
Sparfloxacin is in the FDA pregnancy category C. This means that it is not known whether sparfloxacin will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment. Sparfloxacin passes into breast milk and may harm a nursing infant. It may affect bone development. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. Sparfloxacin is not approved for use by children younger than 12 years of age. Sparfloxacin may interfere with bone development.
How should I take Zagam (sparfloxacin)?
Take sparfloxacin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water (8 ounces). Drink several extra glasses of fluid each day to prevent the formation of sparfloxacin crystals in your urine.
Sparfloxacin may be taken with or without food.
Take sparfloxacin at evenly spaced intervals. Follow your doctor's instructions.
Do not take antacids that contain magnesium or aluminum (e.g., Tums or Rolaids), the ulcer medicine sucralfate (Carafate), or vitamin or mineral supplements that contain iron or zinc for a minimum of 4 hours after a dose of sparfloxacin. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of sparfloxacin can greatly decrease the effects of the antibiotic. Take all of the sparfloxacin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated. Store this medication at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.
What happens if I overdose?
Seek emergency medical attention.
The most common symptom of a sparfloxacin overdose is irregular or slow heartbeats.