What is Lamisil?
Terbinafine is an antifungal antibiotic.
Lamisil is used to treat infections caused by fungus that affect the fingernails or toenails. Lamisil oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old.
Lamisil may also be used for other purposes not listed in this medication guide.
Important information about Lamisil
Before using Lamisil, tell your doctor if you have liver or kidney disease, or an autoimmune disorder such as lupus or psoriasis.
Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Lamisil will not treat a viral infection such as the common cold or flu. Some people taking Lamisil have developed severe liver damage leading to liver transplant or death. It is not clear whether Lamisil actually caused the liver damage in these patients. In most cases, the patient had a serious medical condition before taking Lamisil.
Call your doctor at once if you have symptoms of liver damage, such as nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). These events can occur whether or not you have ever had liver problems before.
To be sure this medication is not causing harmful effects, your blood may need to be tested on a regular basis. Your liver function may also need to be tested. Do not miss any scheduled appointments.
It may take several months for your nails to return to their normal appearance after your treatment with Lamisil.
What should I discuss with my healthcare provider before taking Lamisil?
You should not use this medication if you are allergic to terbinafine:
Before using Lamisil, tell your doctor if you are allergic to any drugs, or if you have:
• liver disease;
• kidney disease; or
• an autoimmune disorder such as lupus or psoriasis.
If you have any of these conditions, you may need a dose adjustment or special tests to safely use this medication.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Lamisil can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take Lamisil?
Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
Take the Lamisil tablet with a full glass (8 ounces) of water.
Lamisil granules should be sprinkled into a spoonful of pudding or mashed potatoes (do not mix with applesauce, fruit juice, or other acidic foods). Swallow this mixture right away without chewing. Do not save the mixture for later use.
The Lamisil granule mixture should be taken with a meal. Lamisil is usually taken for 6 to 12 weeks. Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Lamisil will not treat a viral infection such as the common cold or flu.
To be sure this medication is not causing harmful effects, your blood may need to be tested on a regular basis. Your liver function may also need to be tested. Do not miss any scheduled appointments.
It may take several months for your nails to return to their normal appearance after your treatment with Lamisil.
Store Lamisil at room temperature away from moisture, heat, and light.
Keep the Lamisil oral granules in their sealed packet until you are ready to use.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medication.
Overdose symptoms may include dizziness, stomach pain, nausea, vomiting, skin rash, or urinating more than usual.
What should I avoid while taking Lamisil?
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using Lamisil.
Lamisil side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Some people taking Lamisil have developed severe liver damage leading to liver transplant or death. It is not clear whether Lamisil actually caused the liver damage in these patients. In most cases, the patient had a serious medical condition before taking Lamisil.
Call your doctor at once if you have symptoms of liver damage, such as nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). These events can occur whether or not you have ever had liver problems before.
Stop taking Lamisil and call your doctor at once if you have a serious side effect such as:
• joint pain or swelling, swollen glands, patchy skin color, or a butterfly-shaped skin rash over your cheeks and nose;
• fever, chills, body aches, flu symptoms;
• changes in your vision;
• weight loss due to taste changes;
• scaly, itchy, and flaky skin rash; or
• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash.
Less serious side effects may include:
• stomach pain, heartburn, diarrhea;
• headache;
• tired feeling;
• runny or stuffy nose, sore throat, cold symptoms;
• mild skin rash or itching;
• unusual or unpleasant taste in your mouth; or
• decreased taste sensation.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
What other drugs will affect Lamisil?
Before taking Lamisil, tell your doctor if you are taking any of the following medicines:
• amiodarone (Cordarone, Pacerone);
• cimetidine (Tagamet, Tagamet HB);
• rifampin (Rifadin, Rimactane);
• another antifungal antibiotic, such as fluconazole (Diflucan);
• a blood thinner such as warfarin (Coumadin);
• a heart rhythm medication such as propafenone (Rythmol) or flecainide (Tambocor);
• an "SSRI" antidepressant such as fluoxetine (Prozac), fluvoxamine (Luvox), or paroxetine (Paxil);
• a tricyclic antidepressant such as amitriptyline (Elavil, Etrafon), desipramine (Norpramin), imipramine (Janimine, Tofranil), and others;
• an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate); or
• a beta-blocker such as atenolol (Tenormin, Tenoretic), bisoprolol (Zebeta, Ziac), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), timolol (Blocadren), and others.
This list is not complete and there may be other drugs that can interact with Lamisil. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Where can I get more information?
• Your pharmacist can provide more information about Lamisil.
• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.